FAIRMol

KB_HAT_91

Pose ID 10954 Pose 111

DB SELECTIONDocking pose analysis is being read from this database.
Molecular metrics status: missing
Molecular metrics have not been computed yet for this pose.
No cached metrics
T17
T. brucei TR (Doorstop site) T. brucei Doorstop site
Ligand KB_HAT_91
PDB5S9T

3D complex viewer

Strict H-bonds Permissive H-bonds
Viewer legend
Protein receptor
Pocket residues
Cofactor context
Docked ligand
Overall assessment
Weak Metrics pending
Promising but geometrically suspicious
Binding strong Geometry low Native strong SASA pending
Strain ΔE
32.1 kcal/mol
Protein clashes
10
Internal clashes
10
Native overlap
contact recall 0.75, Jaccard 0.41, H-bond role recall 0.00
Burial
95%
Reason: 10 protein-contact clashes, 10 internal clashes
10 protein-contact clashes 10 intramolecular clashes

Interaction summary

HB 6 HY 24 PI 3 CLASH 10
Final rank5.983Score-55.689
Inter norm-0.724Intra norm-1.017
Top1000noExcludedyes
Contacts19H-bonds6
Artifact reasonexcluded; geometry warning; 10 clashes; 3 protein clashes; very favorable intra outlier; high strain Δ 32.1
Residues
ALA363 ALA365 ARG287 CYS375 FAD501 GLY376 HIS428 ILE199 LEU332 LEU334 LEU377 MET333 PHE198 PHE230 SER162 SER364 THR374 VAL362 VAL366

Protein summary

1033 residues
Protein targetT17Atoms15160
Residues1033Chains2
Residue summaryVAL:1536; LEU:1387; LYS:1386; ILE:1064; GLU:900; THR:868; ARG:816; PHE:800; ALA:780; ASN:700; PRO:686; GLY:672; SER:616; TYR:588; ASP:528; MET:408

Receptor context

2 kept / 0 excluded
Receptor context filtering: interactions and SASA are computed against protein atoms plus allowed cofactors/ions. Native ligand-like HETATM partners are excluded from scoring.
Kept context 2 Excluded HETATM 0
Kept cofactors / ions
A:FAD501 B:FAD501

Native ligand reference

★ reference
Interaction fingerprint calculated directly from the uploaded native ligand without docking. Current H-bond mode: strict.
Name5S9TContacts12
PoseOpen native poseHB0
IFP residues
ALA365 ARG228 ARG331 GLY229 LEU332 LEU334 MET333 PHE198 PHE230 SER364 THR374 VAL366
Current overlap9Native recall0.75
Jaccard0.41RMSD-
HB strict0Strict recall0.00
HB same residue+role0HB role recall0.00
HB same residue0HB residue recall0.00

HB · H-bonds

Mode: strict. Count shows atom-level H-bonds; unique residues in summary: 0.

PI · π–π interactions

Native π–π recall is disabled because no explicit native π–π reference was stored.

HY · Hydrophobic contacts

CLASH · Clashes

All stored poses for this docking hit

PoseFinal rankInter normScoreHBCTCT overlapCT recallHB role rec.RMSDExcluded
111 5.9828840814727835 -0.723526 -55.6894 6 19 9 0.75 0.00 - yes Current

Molecular metrics

RDKit SASA burial, strain energy (MMFF94s), ligand efficiency and fit quality for this docking pose.
⚠ Not yet computed
Molecular metrics have not been computed for this pose yet. This page now reads only cached values; use a background recompute when you want fresh metrics without slowing the UI.